Cryo21 therapy facilitates a thermal shock by reducing the temperature of fat cells, causing them to die-off in a natural way. This natural die-off process is called apoptosis, which results in a gradual degeneration of fat cells and their evacuation of dead fat cells. Apoptosis of fat cells occur when the special device Cryo21 reduces the temperature in the area from 34 °C to 8 °C and without the client feeling cold. After 4-6 treatments it is not unusual for the clients to lose up to 10 cm around the waist or and this is accomplished permanently without any kind of surgery.